Germ Cell Tumors
Overview
Germ cell tumors are growths that come from cells that develop into eggs in females or sperm in males. These tumors can be benign or malignant and can occur in the reproductive organs (like the ovaries or testes) or in other parts of the body, like the chest, abdomen, or brain.
Common signs and symptoms
- Testicular lump or swelling
- Abdominal pain or swelling due to ovarian mass; may lead to abnormal vaginal bleeding or precocious puberty
- Extragonadal tumors: Can cause back pain (if in the sacrococcygeal area), respiratory distress (if in the chest), or gastrointestinal symptoms (if in the abdomen)
- Fatigue, weight loss, and fever
Diagnostic tests and procedures
Physical Examination
Assessment of lumps or swelling in the affected area.
Imaging studies
Imaging studies like Ultrasound, CT scan and MRI.
Blood Tests
Measurement of tumor markers such as: Alpha-fetoprotein (AFP), Beta-human chorionic gonadotropin (β-hCG), Lactate dehydrogenase (LDH) and others.
Biopsy:
Tissue sample taken for histological examination to confirm diagnosis.
The Journey of Healing Starts Here
If you or your loved one is experiencing symptoms of Germ cell tumors, our expert hematology team is here to help. We provide comprehensive diagnostic services, individualized treatment plans, and ongoing support to ensure the best outcomes.
Treatment options
Surgery
Primary treatment for localized tumors; involves removal of the tumor and affected tissue.
Chemotherapy
Often used for malignant germ cell tumors.
Radiation Therapy
May be used for certain types of germ cell tumors.
Prognosis
The prognosis usually varies based on factors such as the tumor’s type, location, and whether it has spread. Many children respond well to treatment, especially when the tumor is detected early.