Apheresis Program
Overview
Apheresis Program plays a vital role in the care of patients with blood disorders, cancer, and those undergoing bone marrow or stem cell transplantation. Apheresis is a specialized procedure that safely removes or collects certain components from the blood, such as white blood cells, plasma, platelets, or stem cells, depending on the patient’s medical needs.
This treatment is performed using an advanced machine that separates blood into its individual parts, allowing only the needed component to be removed while the rest is returned to the body. It is used for a variety of reasons, such as collecting stem cells for transplant, reducing high white blood cell counts, removing disease-causing antibodies, or collecting donor cells for patients in need of a transplant.
Our team ensures that each procedure is carefully monitored, comfortable, and safe. We also offer apheresis support for both pediatric and adult patients, and our services are fully integrated into the broader treatment plans developed by our team. Through this program, we aim to provide life-saving care using cutting-edge technology and compassionate support.
Peripheral Blood Stem Cell Collection
Peripheral Blood Stem Cell Collection is an important part of the treatment process for certain cancers and blood disorders, especially for patients who need a stem cell or bone marrow transplant. Instead of taking stem cells from the bone marrow through surgery, we can now collect them directly from the bloodstream in a safe, non-surgical way.
Preparing Your Body
For five days before the donation, you’ll receive a medication called G-CSF through a small injection under the skin. This helps your body produce extra stem cells and move them into your bloodstream. Some people feel mild flu-like symptoms during this time, such as bone aches, headaches, or fatigue—these go away soon after the donation.
The Donation Day
On the day of your donation, you’ll be comfortably seated in a reclining chair while your blood is drawn through one arm, passed through a machine that separates out the stem cells, and then returned to your other arm. The procedure usually lasts 4–6 hours. Most donors can read, watch movies, or even nap during the session.
After Donation
You can go home the same day. Some people feel tired afterward, but most return to normal activities within a day or two. The stem cells your body gave are naturally replaced within a few weeks.
You are in Good Hands
Throughout the process, our team of healthcare professionals will be there to guide, support, and monitor you. Your safety and comfort are our top priority. The collection procedure is non-invasive, well-tolerated, and has been safely performed thousands of times around the world.
By donating, you’re giving more than just cells, you’re offering hope to a patient in need of a life-saving transplant. Thank you for considering this incredible act of kindness.
Automated Plasma Exchange (Therapeutic Plasmapheresis)
Indications
Used for autoimmune disorders (e.g., Guillain-Barré syndrome, myasthenia gravis), neurological conditions, thrombocytopenic purpura and to manage rejection after organ transplants.
Procedure
Blood is drawn from the patient, processed through a machine that separates the blood cells from the plasma, and the remaining components are then mixed with a replacement solution, such as saline or donor plasma, before being reintroduced into the patient’s body. The undesirable plasma, which may contain harmful substances, is discarded. This procedure is typically performed multiple times based on individual patient needs.
Our apheresis machines ensure precise plasma separation while maintaining patient comfort. Each session lasts approximately 2 to 4 hours, during which we monitor vital signs closely to ensure safety and efficacy. Our trained staff provides comprehensive pre- and post-procedure care, ensuring that patients are well-informed about the process and its benefits.
Prognosis
The outcomes for patients undergoing plasmapheresis can vary based on the underlying condition being treated. When it is integrated into a comprehensive treatment plan, many patients experience significant improvements in their symptoms and health.
T-cell Collection by Apheresis
Definition
T cell collection by apheresis is a procedure to collect T-cells from a donor or patient’s blood for therapeutic use.
Indications
Commonly used in treatments for certain cancers and immune disorders.
Procedure
T cell collection by apheresis is a specialized procedure designed to extract T cells, a type of white blood cell that is vital for the immune response. Blood is drawn and processed using an apheresis machine to isolate T-cells for further modification or treatment. During apheresis, blood is drawn from the patient through a needle in one arm and processed through a machine that separates the T cells from other blood components. The machine collects the T cells while returning the remaining components, including red blood cells and plasma, back to the patient through a needle in the other arm. Collected T-cells can be expanded and reintroduced into the patient after further processing and modification.
Red Blood Cell Exchange (RBC Exchange)
Definition
Red Blood Cell Exchange is a procedure that replaces abnormal red blood cells with healthy donor red blood cells.
Indications
Red Blood Cell Exchange is primarily used in sickle cell disease and certain infections where red blood cells are dysfunctional.
Procedure
Blood is drawn from one arm, abnormal red blood cells are separated out using a centrifuge, and healthy red blood cells are infused back into the patient. It typically lasts 1 to 2 hours; may require multiple exchanges depending on the patient’s condition. We focus on minimizing discomfort while effectively replacing abnormal red blood cells with healthy cells. Continuous monitoring during the procedure ensures patient safety and optimal outcomes.
Leukopheresis
Definition
Leukopheresis is a procedure that selectively removes white blood cells (leukocytes) from the blood.
Indications
Leukopheresis is used in conditions like chronic lymphocytic leukemia or severe leukocytosis to reduce high white blood cell counts.
Procedure
Blood is drawn, leukocytes are separated out using an apheresis machine, and the remaining components are returned to the patient. This procedure is performed with care and precision, helping to alleviate symptoms associated with high leukocyte counts.
T-cell depletion (TCD)
Definition
T-cell depletion involves the selective removal of specific T cells from the donor’s stem cell graft before it is infused into the patient.
Indications
TCD is used to reduce the risk of GVHD, to improve immune Reconstitution and gives access to more donors.