Rhabdomyosarcoma (RMS)

Overview

Rhabdomyosarcoma (RMS) s a rare cancer that develops in soft tissues, most often affecting children and teens. It starts in cells that normally grow into skeletal muscles but become cancerous instead.

Common signs and symptoms

  • Bulging eyes, headaches, nosebleeds, or ear discharge if the tumor grows in the head or neck
  • Belly pain, vomiting, or constipation if it is in the abdomen
  • Trouble urinating, blood in urine, or vaginal bleeding if it grows in the urinary/reproductive system
  • Firm masses in arms or legs; may cause pain if pressing on nerves
  • Fatigue, weight loss, and systemic signs like fever may occur in advanced cases

Diagnostic tests and procedures

Physical Examination

To identify lumps and evaluate symptoms.

Imaging Studies

like Ultrasound, CT Scan/MRI to assess tumor size, location, and potential metastasis, and PET Scan to detect spread.

Biopsy

To obtain a tissue sample for histological examination to confirm diagnosis.

Treatment options

  • Chemotherapy is the cornerstone of treatment and is usually started early.
  • Surgery aims for complete removal but avoids functional or cosmetic harm.
  • Radiotherapy is used for high-risk cases or when complete tumor removal isn’t possible.

Prognosis

Prognosis depends on factors like tumor size, spread, location, and histology. Localized tumors in favorable areas have a better chance of recovery. Advanced cases with metastasis have a poorer prognosis.

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