Juvenile Myelomonocytic Leukemia (JMML)
Overview
JMML is a rare blood cancer that mostly affects children under 4 years old. It happens when the bone marrow makes too many abnormal white blood cells (monocytes and myelocytes). These cells crowd out healthy blood cells, making it hard to fight infections, stop bleeding, or stay energized.
Common signs and symptoms
- Persistent fatigue
- Unexplained fevers
- Night sweats
- Easy bruising or bleeding
- Bone or joint pain
- Swollen lymph nodes, liver and spleen
- Pallor
Diagnostic tests and procedures
- Complete blood count (CBC) can reveal abnormalities in blood cell levels indicative of leukemia.
- Bone marrow aspiration and biopsy to check for cancerous cells .
- Further tests like flow cytometry and genetic tests to predict prognosis and choose the best treatment.
- Imaging like X-rays or CT scans.
- Peripheral blood smear to look for abnormal cells.
The Journey of Healing Starts Here
If you or your loved one is experiencing symptoms of Juvenile Myelomonocytic Leukemia, our expert hematology team is here to help. We provide comprehensive diagnostic services, individualized treatment plans, and ongoing support to ensure the best outcomes.
Treatment options
Bone marrow transplant (BMT)
It is considered the most effective treatment for JMML. This procedure replaces diseased bone marrow with healthy stem cells from a donor.
Targeted therapy
Targeted therapy that specifically target genetic abnormalities in their leukemia cells.
Supportive care
Including blood transfusions, antibiotics for infections, and other medications.
Prognosis
The prognosis for JMML can be challenging due to its aggressive nature, advancements in treatment and careful management can improve outcomes for many patients. Regular follow-up and monitoring are essential for managing this complex condition effectively.